A RESEARCH PROPOSAL: COMBINATORIAL NOVEL DRUG DELIVERY APPROACH OF THE MANAGEMENT OF ACNE-VULGARIS

Abstract

Chronic skin illness known as acne vulgaris is
mostly brought on by obstructions in the
sebaceous glands or inflammation in those
glands, which are collectively referred to as
pilosebaceous units. It mostly affects the face,
back, and upper chest, which are the regions
with the greatest concentration of sebaceous
follicles. This illness may strike anyone of any
age, although it mostly affects adolescents.
These may manifest as non-inflammatory closed
comedones (whiteheads), open comedones
(blackheads), inflammatory pustules, papules,
cysts, and nodules, or a combination of
symptoms. It is most usual for practically
everyone to have acne at some time in their life.
There are 20–25 percent odds that acne may
worsen to the point where it leaves permanent
scars. Psychological issues including sadness,
social isolation, poor self-esteem, and low self-
confidence are brought on by these obstacles.
The purpose of acne treatment is to avoid
serious, long-term consequences. The innovative
medication delivery methods for the treatment of
acne are the main topic of this review. It also
covers the limits of the traditional medicines that
are now on the market, as well as other
approaches to get around them.