Analysis of the Buccal Patch Drug Delivery System, Development, and Clinical Trials.

Abstract

The mouth is a promising medication delivery location because drugs taken orally bypass the
digestive system and first-pass metabolism, where they might be degraded. Delivery of medications via the
buccal mucosa to produce systemic pharmacological effects is what is meant by the term "buccal drug
delivery."Advantages of buccalbioadhesive films over conventional dosage forms may be seen in the treatment of
numerous disorders due to the controlled and gradual release of topical medications in the mouth cavity.The
buccal patch is a non-dissolving, thin-matrix, modified-release dosage form designed for the supine and
uncooperative patient.[1] The buccal mucosa's accessibility, smooth, and inflexibility make it an ideal location
for a bioadhesion system. Consequently, medications having a limited half life in the body. Oral flexible patches
have been created to address the problems associated with taking pills. The purpose of this review is to educate
readers about buccal patches and the buccal medication delivery mechanism. Review the criteria used to assess
buccal patches