An Improved Method for Gastro-Retentive Drug Delivery Using Micro balloons

Abstract

The administration of drugs in the form of microballoons orally is the most common and preferred
method. Gastric retention by use of microballoons is proposed as a viable option. Non-effervescent systems
comprising empty spherical particles without a center, ideally measuring fewer than 200 micrometers in
diameter, are the basis for the microballoon drug delivery method. Floating medicine delivery using
microballoons has recently emerged as a promising new topic in the pharmaceutical industry. Microballoons, or
hollow microspheres, have a number of other names. Microballoons are a smooth, breathable material that floats
well in stomach juice. The medicine is retained in the stomach thanks to the microballoons. It's able to discharge
its contents slowly and steadily. Microballoons are unfilled spherical vehicles. That can maintain its buoyancy in
the stomach for an extended amount of time without irritating the intestines. GRDDS, benefits, drawbacks,
methods of production of microballoons, applications, and assessment procedures are all discussed in depth as
they relate to the physical characteristics of microballoons.