Therapeutic Potential of Targeting IncRNA-Mediated Epigenetic Modification's in Liver Fibrosis

Abstract

Excessive growth of connective tissue in an organ that is prone to cirrhosis is the hallmark of the dangerous condition known as liver fibrosis. New approaches to the diagnosis and therapy of liver fibrosis can only be developed by first understanding the processes that cause this illness to progress. There is mounting evidence that a subset of RNAs known as long non-coding RNAs (lncRNAs) contribute significantly to the development of liver fibrosis and might represent promising new treatment targets. This article provides a comprehensive overview of long non-coding RNAs (lncRNAs) in liver fibrosis, including their function, pathogenetic pathways, relevant investigations, and potential diagnostic markers and therapeutic targets. Potentially ground-breaking methods for detecting and treating liver fibrosis may emerge from the discovery and investigation of these lncRNAs. To identify lncRNAs as possible biomarkers and treatment targets and to comprehend the molecular pathways linked to liver fibrosis, more study is required.