Phytochemical analysis, traditional applications, Pharmacology and toxicity of Thymus serpyllum

Abstract

The Lamiaceae family understudied perennial plant Thymus serpyllum L. has a long history of use in the
treatment of gastrointestinal and respiratory disorders in the higher foothills of India. Our present
understanding of T. serpyllum traditional applications, phytochemistry, and pharmacology is not well-
rounded, and that is the goal of this review. Gathering up-to-date knowledge on this plant is our top
priority, as is promoting more in vivo and in vitro studies to back up local claims. Due to its varied
pharmacological qualities, such as antioxidative, antibacterial, anti-inflammatory, and anticancer activity,
the essential oil extracted from T. serpyllum has garnered substantial interest as a plant-derived product.
When it comes to creating novel medications to tackle a wide range of health sector issues,
ethnomedicinal research has shown that T. serpyllum has a lot of potential. Pharmacological
investigations alone are insufficient to support the widespread usage of T. serpyllum. In most cases,
researchers use either in vitro or in vivo methods. To evaluate these medical assertions, more research is
needed in the form of carefully orchestrated pharmacological trials. The findings of this evaluation will
serve as a springboard for more studies. Despite T. serpyllum extensive traditional usage, there has been
a dearth of pharmacological research, with the majority of investigations conducted in either in vitro or
in vivo settings. Important topics to explore include further chemical isolation, thorough pharmacological
study, and potential culinary uses.