Examination of the rectangle apparatus developed by Asyogh for the purpose of assessing memory and learning in Wistar rats

Abstract

The purpose of this research was to develop an improved version of Asyogh's rectangle gadget
for evaluating rodent memory. Increased transfer latency times shown that rats significantly
impaired in memory when administered scopolamine (3 mg/kg i.p.) and diazepam (1 mg/kg i.p.).
But when the rats were given Donepezil beforehand, their memory problems disappeared.
Thanks to the considerable improvement in TLT, it's clear that pretreatment donepezil may
successfully reverse the memory impairments caused by scopolamine and diazepam. This
research demonstrated that the device used to detect transfer delay time was an effective
instrument for evaluating cognitive function and memory in rats.